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| p981204a - Cocaine - Metabolism | |||
| Cocaine - Metabolism 12/04/98 (Kokko) Question: How is cocaine metabolized? 1 [Use Link to view the full text] Unique Identifier 90289785 Authors: Kokko JP. | |||
| http://www.emory.edu/WHSCL/grady/amreport/litsrch98/p981204a.html |
| Butyrylcholinesterase | |||
| Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans by Carmona GN, Jufer RA, Goldberg SR | |||
| http://cocaine.org/butyrylcholinesterase/ |
| Cocaine and benzoylecgonine | |||
| Mechanisms of cocaine hydrolysis and metabolism in vitro and in vivo: a clarification by Warner A, Norman AB Department of Pathology and Laboratory Medicine | |||
| http://cocaine.org/metabolism/ |
| NIDA Monograph 173, pp. 35-47 | |||
| Page 1. 35 Effects of Ethanol on Cocaine Metabolism and Disposition in the Rat Robert A. Dean, William F. Bosron, Frederick M. Zachman, Jing Zhang, and Monica R | |||
| http://www.drugabuse.gov/PDF/Monographs/Monograph173/035-047_Dean.pdf |
| NIDA NOTES - Blood-borne Medications Could Intercept Drugs Before ... | |||
| in BChE activity significantly decreased the increased motor activity caused by a cocaine injection and changed the pattern of cocaine metabolism, resulting in | |||
| http://www.drugabuse.gov/NIDA_Notes/NNVol14N2/medications.html |
| Cocaine, (DELETED) Dimorphisms and P450 Activity | |||
| dimorphic response. This differential quality is particularly clear in the case of cocaine metabolism. Cocaine forms hepatotoxic | |||
| http://home.earthlink.net/~cpardee/drugs.html |
| ODCCP - Bulletin on Narcotics - 1965 Issue 2 - 002 | |||
| Metabolism of cocaine. Sections. Summary Details. Other writers also indicate benzoyl-ecgonine as the final product of cocaine metabolism. | |||
| http://www.undcp.org/odccp/bulletin/bulletin_1965-01-01_2_page003.html |
| Recent advances in enzymatic hydrolysis with immobilized enzymes ... | |||
| In order to investigate the influence of hepatic esterases on cocaine metabolism in contrast to the plasmacholinesterase, the model of the isolated serum-free | |||
| http://www.tiaft.org/tiaft2001/lectures/l43_toennes.doc |
| SOFT/TIAFT 98 - Cocaine Transport and Metabolism by the Colonic ... | |||
| COCAINE TRANSPORT AND METABOLISM BY THE COLONIC T84 EPITHELIAL CELL LINE Results Cocaine incubated with media alone for 30 and 60 min showed no metabolism. | |||
| http://www.tiaft.org/tiaft98/thu/p/t_p_31.html |
| APStracts 5:0345R, 1998. | |||
| It has been suggested that toxicity to cocaine is related to the relative rate of cocaine metabolism by cholinesterases and to activation of cholinergic | |||
| http://oac3.hsc.uth.tmc.edu/apstracts/1998/regulatory/September/345R.html |
| AJP: Endocrinology and Metabolism Table of Contents | |||
| ... AJP: Endocrinology and Metabolism, Dept. of Medicine and the Dept of Physiology, University of Alberta,... 48105, ph: 313-996-3960, fax: 313-996-5668 APStracts 2:0223E, 1995. Cocaine and exercise: temporal changes in the plasma | |||
| http://www.uth.tmc.edu/apstracts/1995/endo/November/toc.html |
| Selegiline and cocaine-induced euphoria | |||
| Selegiline effects on cocaine-induced changes in medial temporal lobe metabolism and subjective ratings of euphoria by Bartzokis G, Beckson M, Newton ...-B) inhibitor, on the cerebral metabolic and euphorigenic effects of cocaine- | |||
| http://selegiline.com/cokedep.html |
| The Physiology and metabolism of Cocaine | |||
| ... Smoking Gambling Co-Dependency Rebuild Family's The PHYSIOLOGY of CocaineCocaine use. Local anesthetics used in dentistry are variations of the ...Koob, 1994). Cocaine has similar effects on serotonin, and alters the metabolism | |||
| http://www.druginfo4u.net/physiology_of_cocaine.htm |
| Narconon® Drug Addiction Treatment Program: Precipitation of Cocaine | |||
| ...™ The World’s Most Successful Drug Rehab. The Precipitation of Cocaine metabolites may ac(DELETED)ulate in the body and that several days to ...study suggests sauna baths and other methods to increase sweating and metabolism may preci(DELETED) | |||
| http://www.usnodrugs.com/cocaine_metabolites_presented_by_n.htm |
| to 7:54, metabolism of cocaine | |||
| ... articles or replies. No messages are screened for content. to 7:54, metabolismof cocaine This response submitted by on 11/24/99. Email Address: from 11:34. ...If you are saying that ritalin and cocaine as quickly, okay. That's | |||
| http://neuro-www.mgh.harvard.edu/forum_2/ADHDF/to7.54metabolismofcocaine.html |
| Medically Approved detox for marijuana, cocaine, THC, to use at home? | |||
| ...more extensive program for the heavy user. This program can help your metabolism slowly and gently extract contaminants from your system in as little as 4 days and as much as up to 10 days. Depending on individual cir(DELETED)stances. Call our | |||
| http://detoxit.com/products.htm |
| Botany online: The Secondary Metabolism of Plants - Cocaine | |||
| Cocaine © Peter v. Sengbusch - b-online@botanik.uni-hamburg.de | |||
| http://www.biologie.uni-hamburg.de/b-online/e20/cocain.htm |
| Botany online: The Secondary Metabolism of Plants - Cocaine | |||
| ... Search Engine Cocaine © Peter v. Sengbusch - b-online@botanik.uni-hamburg.de | BACK HOME | |||
| http://www.i-a-s.de/IAS/botanik/e20/cocain.htm |
| COCAINE AND STIMULANTS | |||
| ...Naltrexone Substance Abuse Library Community Center Alcohol News MENU COCAINE Cocaine has had two periods of popularity in the United States ...when supplies of the drug are exhausted. The major route for cocaine metabolism involves | |||
| http://www.med.upenn.edu/recovery/pros/cocaine.html |
| Robert S Hoffman, MD | |||
| Medical Toxicology). Medical Specialty: Emergency Medicine. Research Interests: Cocaine Metabolism: Search for an Antidote. At epidemic | |||
| http://www.med.nyu.edu/ERWeb/faculty/hoffman.html |
| Viewbook- David Gorelick | |||
| Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy. DA Gorelick. Drug and Alcohol Dependence 48:159-165(1997). | |||
| http://gpp.nih.gov/researchers/viewbook/Gorelick_David.html |
| Motherisk | |||
| A, Derewlany LO, Knie B, Koren G: The effects of cocaine and nicotine Challis DE, Pfarrer CD, Ritchie JW, Koren G, Adamson SL: Glucose metabolism is elevated | |||
| http://www.motherisk.org/pharma/index.php3 |
| Cocaine N-demethylation and the metabolism-related hepatotoxicity ... | |||
| Alhava E, Pelkonen O, Lang MA, Pasanen M. Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors. | |||
| http://www.uku.fi/wwwdata/julkaisutoiminta/julkaisut/1994/9400632.html |
| Biochemical Society Transactions Home Search Feedback Links Join ... | |||
| approach to drug metabolism and endogenous function 09:40-10:20 Matt Redinbo (North Carolina, USA) Structural basis of heroin and cocaine metabolism by the | |||
| http://www.biochemistry.org/meetings/programme.cfm?meetno=SA010 |
| New addiction research unlikely to be applied | |||
| Although dopamine metabolism has been a major focus of research on cocaine metabolism, researchers sponsored by the National Institute on Drug Abuse (NIDA | |||
| http://www.nature.com/cgi-taf/DynaPage.taf?file=/nm/journal/v7/n7/full/nm0701_757.html |
| Lessons from a bacterial cocaine esterase | |||
| Moreover, the enzyme is inducible 7 and relatively specific for cocaine, making it a particularly useful enzyme for the study of cocaine metabolism. | |||
| http://www.nature.com/cgi-taf/DynaPage.taf?file=/nsb/journal/v9/n1/full/nsb0102-4.html |
| Research Interests of Stephen M. Roberts, Ph.D. | |||
| The role of cocaine metabolism in toxicity is being explored, as well as drug interactions that might increase susceptibility to liver toxicity from cocaine. | |||
| http://www.mbi.ufl.edu/physdept/smrreshe.htm |
| How Long Does it Take for Cocaine to Clear Out of Urine? | |||
| cocaine is being abused by a caller, it seems that a broader range of potential detection times should be given when explaining cocaine metabolism in regard to | |||
| http://www.druglibrary.org/schaffer/cocaine/clearurine.htm |
| COCAINE AND STIMULANTS | |||
| The major route for cocaine metabolism involves hydrolysis of each of its two ester groups resulting in loss of pharmacological activity. | |||
| http://www.uphs.upenn.edu/recovery/pros/cocaine.html |
| Program Book - Peripheral Blockers as Treatments - Program List | |||
| 11:00 am - 11:30 am, Enhancing Cocaine Metabolism With Butyrylcholinesterase as an Approach to Cocaine Addiction Treatment, David A. Gorelick, MD, Ph.D. National | |||
| http://www.nida.nih.gov/MeetSum/Peripheral/program.html |
| NIDA Monograph 173: Pharmacokinetics, Metabolism, and Pharmaceutics of Drugs of Abuse | |||
| Common Drugs of Abuse. Acid/LSD. Alcohol. Cocaine. Club Drugs. Drug Testing. Heroin. Inhalants. Marijuana. MDMA/Ecstasy. Methamphetamine. Nicotine. PCP (Phencyclidine) Prescription Medications. | |||
| http://www.nida.nih.gov/PDF/Monographs/Monograph173/Download173.html |
| Protein Spotlight | |||
| There they discovered Rhodococcus . A closer look at the bacterium revealed an enzyme, cocaine esterase, which is at the heart of cocaine metabolism. | |||
| http://us.expasy.org/spotlight/articles/sptlt027.pdf |
| Rhodococcus: Natures junkie | |||
| There they discovered Rhodococcus. A closer look at the bacterium revealed an enzyme, cocaine esterase, which is at the heart of cocaine metabolism. | |||
| http://us.expasy.org/spotlight/articles/sptlt027.html |
| TEMPLATE | |||
| Abstract. Cocaine. Cocaine - Metabolism 12/04/98 (Kokko). Question: How is cocaine metabolized? - Presidential address of the SSCI. | |||
| http://www.emory.edu/WHSCL/grady/amreport/rr_social.html |
| World Wide Web Resources for Social Workers | |||
| Biocatalysts in Detoxication of Drugs of Abuse. Effects of Ethanol on Cocaine Metabolism and Disposition in the Rat. Human Liver Cocaine Carboxylesterases. | |||
| http://www.nyu.edu/cgi-bin/cgiwrap/jep7/demomenu.cgi?cid=7208 |
| Eppley Institute | |||
| 137: 43-54. Sun H, Shen M, Pang YP, Lockridge O, Brimijoin S (2002) Cocaine hydrolase engineered from human BChE accelerates cocaine metabolism in rats. | |||
| http://www.unmc.edu/Eppley/publications/pub_lock.html |
| eMedicine - Topical Anesthetics, Cocaine : Article by Don R Revis ... | |||
| Oxidative metabolism in the liver produces norcocaine, a toxic substance capable of causing severe hepatic damage. Approximately 5% of absorbed cocaine is | |||
| http://www.emedicine.com/ent/topic384.htm |
| Coca, cocaine and (DELETED) | |||
| immunization; Cocaine/Merck; Cocaine metabolism; Cocaine/monoamines; Cocaine mules; Cocaine/N America; Cocaine/ophthalmology; Cocaine : structure; | |||
| http://www.cocaine.org.uk/refs/ |
| EAPP2 | |||
| Detection time : Up to 6 (cocaine) and 60 h (benzoylecgonine); up to 60 days (metabolites) after chronic daily use. Fig. 10 : Metabolism of Cocaine. | |||
| http://www.ichv.ch/AGSA/E/EAPP2.htm |
| Cocaine | |||
| The two main metabolites, ecgonine methyl ester and benzoylecgonine account for up to 90% of cocaine metabolism, and are excreted in urine. | |||
| http://psychology.unn.ac.uk/mark/PY116/HPcocaine/HPCOCAINE.htm |
| Stimulants, Sedatives and Other Drugs | |||
| Cocaethylene * Psychoactive substrate from EtOH+cocaine * EtOH before cocaine inhibits cocaine metabolism, producing cocaethylene * 60-90% of cocaine abuser | |||
| http://www.bumc.bu.edu/www/busm/care/images/stimulants.pdf |
| Enzyme Reactions (Reference: Calculus Using Mathematica ... | |||
| that b = the initial [z]. Thus, ds/dt = -r[z initial ] By finding appropriate data on cocaine metabolism, you can now start a very interesting project. | |||
| http://nths.newtrier.k12.il.us/academics/science/~goralb/modeling/enzyme_rex.pdf |
| dowe | |||
| Prenatal cocaine depressed cerebral glucose metabolism in adult males while postnatal cocaine enhanced metabolism in adult females. | |||
| http://138.5.102.102/pharmacology/dowe.htm |
| Nati Dumaual | |||
| Effects of Ethanol on Cocaine Metabolism: Formation of Cocaethylene and Norcocaethylene. Effects of Ethanol on Cocaine Metabolism and Disposition. | |||
| http://www.iupui.edu/~iutox/Academic/nati_dumaual1.htm |
| Consideratrion for cocaine use in Sport.pub | |||
| munity develops to the effects of cocaine following re- peated administration, and because of the large vari- ability in cocaine metabolism between individuals | |||
| http://www.sportfocus.ca/web/pdfs/Consideratrionforcocaineuse.pdf |
| POSTULATED AND ACTUAL INTERACTIONS BETWEEN RECREATIONAL DRUGS AND ... | |||
| metabolic pathways involved in cocaine metabolism; risk may be higher if patient is cholinesterase deficient. Increased levels of | |||
| http://www.tthhivclinic.com/pdf/Recdrug2.pdf |
| Botany online: The Secondary Metabolism of Plants - Cocaine | |||
| Cocaine. © Peter v. Sengbusch - b-online@botanik.uni-hamburg.de. ---- | |||
| http://forestis.rsvs.ulaval.ca/IBC99/B_ONLINE/e20/cocain.htm |
| The Phytochemical World: Cocaine | |||
| An introduction to plant secondary metabolism: flavonoids, alkaloids, phenylpropanoids, and terpenoids. Descriptions of some common plant chemistry phenomena. Includes QuickTime movies of the | |||
| http://www.looneyware.com/pchem/files/case_studies/000029.php |
| Songroth | |||
| PET scans were used to measure brain glucose metabolism in cocaine abusers. One to six weeks following cocaine withdrawal, patients | |||
| http://www.indstate.edu/thcme/anderson/as.html |
| Dr. Nahas - Drug Abuse in the Decade of the Brain - About the ... | |||
| of Cannibas Users, N. Solowij, P. Michie and A. Fox · Cocaine and the Brain: Cocaine: Pharmacokinetics, Metabolism, and Brain Distribution, W. Hearn; Cocaine | |||
| http://www.marijuana-research.com/nyu02.htm |
| CNS stimulants in sport : amphetamine, cocaine and caffeine | |||
| baseball. Cocaine increases tolerance to intense exercise, yet most of its chronic effects on energy metabolism are negative. Its | |||
| http://amphetamines.com/psychostimulants/stimulant.html |
| Miscellaneous Substances, drugs, cocaine, heroin, and fiber | |||
| The anorexigenic effects of cocaine as well as its metabolism cause deficiencies of most water soluble vitamins. Studies have demonstrated | |||
| http://www.diet-and-health.net/Nutrients/miscellaneous.html |
| Methadone Once-A-Day Detox | |||
| of action and steadier blood levels may help assuage cocaine use. not uncommon among such populations, and rifampin enhances the hepatic metabolism of methadone | |||
| http://www.powerpak.com/PowerGraphs/1998/December/methadone.cfm |
| Radioisotope Production | |||
| Dopamine metabolism is also reduced in chronic cocaine abusers (measured with 6-[18F]fluoro-L-DOPA). (See Fowler, et al. for review). | |||
| http://www.crump.ucla.edu/lpp/radioisotopes/tracers.html |
| Clinical Pharmacology Therapeutics Research Branch - Clinical ... | |||
| Synopsis of Research Pharmacokinetic approach to cocaine addiction treatment Enhancing cocaines rate of metabolism or clearance from the body could be a | |||
| http://www.nida.nih.gov/DIR/clinicalpharm.html |
| NIH Guide: NOVEL PHARMACOTHERAPIES FOR COCAINE AND OTHER ... | |||
| biochemical mechanism relevant for behavioral outcomes for cocaine dependence (eg vitamins and supplements that modify neurotransmitter metabolism and energy | |||
| http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-96-003.html |
| eMedicine - Toxicity, Cocaine : Article by Carlos J Roldan, MD | |||
| EME is generated by deesterification of cocaine by the liver and plasma pseudocholinesterases and accounts for 30-50% of cocaine metabolism. | |||
| http://www.emedicine.com/MED/topic400.htm |
| 100 COCAINE | |||
| 1994. Effects of cocaine on glycogen metabolism and endurance during high intensity exercise. Medicine and Science in Sports and Exercise. 26: 695-700. | |||
| http://nutrition.ucdavis.edu/olympics/Drugs/drg6coc.htm |
| Cocaine (PIM 139) | |||
| Barceloux, 1988). 6.4 Metabolism Cocaine metabolism takes place mainly in the liver, within 2 hours of administration. The rate | |||
| http://www.inchem.org/do(DELETED)ents/pims/pharm/pim139e.htm |
| Drug metabolism Drug Interactions between HIV and Recreational ... | |||
| Some drugs, such as smokable cocaine or nitrous oxide, are metabolized so quickly that the body can become so busy metabolizing one drug that metabolism of the | |||
| http://www.hafci.org/drugs/metab.htm |
| The Haworth Press Online Catalog: Product: Alcoholism, Drug ... | |||
| Caffeine; Chapter 14. Cocaine; Patterns of Use; Cocaine Metabolism; Dependency, Tolerance, and Addiction; Adverse Effects of Cocaine; | |||
| http://www.haworthpressinc.com/store/product.asp?sku=4526 |
| Cocaine | |||
| (5). The pharmacokinetics of cocaine metabolism and elimination shows great intra- and interindividual variation. Cocaine undergoes | |||
| http://www.maripoisoncenter.com/ctr/9505cocaine.html |
| ClearChoiceofNewYork.com - cocaine test | |||
| cocaine test metabolism, strength and amount of toxins ingested and for how long the toxins were ingested. HAIR DRUG INFORMATION. | |||
| http://www.clearchoiceofny.com/cocaineltestl.htm |
| Cholinesterase | |||
| CHOLINESTERASE VARIANTS AND COCAINE METABOLISM. Individual response to cocaine is highly variable, with death reported after exposure | |||
| http://www.maripoisoncenter.com/ctr/9504cholinesterases.html |
| dowe | |||
| of the relationship between cocaine and gonad status with gonadectomy reducing metabolism in the controls and cocaine increasing metabolism primarily in | |||
| http://www.hscbklyn.edu/pharmacology/dowe.htm |
| Posters2 | |||
| With respect to cocaine metabolism, two human liver carboxylesterases, designated hCE-1 and hCE-2, catalyze hydrolysis of the methyl and benzoylester linkages | |||
| http://www.ies.krakow.pl/konferencje/tiaft99/abstracts/posters2.htm |
| COCAINE AND ALCOHOL: EFFECTS MORE PRONOUNCED THAN | |||
| The authors of the study concluded that high levels of ethanol have a inhibitory effect on cocaine metabolism to an inactive compound (Chen and West 1998). | |||
| http://sulcus.berkeley.edu/mcb/165_001/papers/manuscripts/_468.html |
| Edward Sherer | |||
| S, Pang YP JOURNAL OF BIOLOGICAL CHEMISTRY 276 (12): 9330-9336 MAR 23 2001 Abstract: Butyrylcholinesterase (BChE) is important in cocaine metabolism, but it | |||
| http://pollux.chem.umn.edu/~sherer/cite_cv5.html |
| Cocaine Metabolite | |||
| 1977;22:697. 7. Stewart DJ, et al. Cocaine metabolism: Cocaine and norco- caine hydrolysis by liver and serum esterases. Clin Pharmacol Ther. 1979;25:464. | |||
| http://www.roche.com.br/diagnostica/lab_system/download/pdf/bulas/bioquimica/mdrogabu/700/COCA.pdf |
| Cocaine Metabolite | |||
| 1977;22:697. 7. Stewart DJ, et al. Cocaine metabolism: Cocaine and norcocaine hydrolysis by liver and serum esterases. Clin Pharma-col Ther . 1979;25:464. | |||
| http://www.roche.com.br/diagnostica/lab_system/download/pdf/bulas/bioquimica/mdrogabu/400/COCA.pdf |
| Imaging studies on the role of dopamine in cocaine reinforcement ... | |||
| In order to test this hypothesis, we assessed the effects of intravenous MP on regional brain glucose metabolism in cocaine abusers using PET and FDG (Volkow | |||
| http://www.sagepub.co.uk/journals/details/issue/sample/a010377.pdf |
| Cocaine Metabolite | |||
| 1977;22:697. 7. Stewart DJ e altri. Cocaine metabolism: Cocaine and nor- cocaine hydrolysis by liver and serum esterases. Clin Pharmacol Ther. 1979;25:464. | |||
| http://www.roche-diagnostics.it/I_400_plus/Dat/coca10-i.pdf |
| Louis Shuster: Sackler School: Tufts University | |||
| Related projects deal with the role of cocaine metabolism in liver damage from cocaine, and genetic determinants of the responses of mice to drugs of abuse. | |||
| http://www.tufts.edu/sackler/facultyIntros/shusterL.html |
| Student Handbook, 2001-2002] DEPARTMENT OF ANESTHESIOLOGY | |||
| 5-6484, 5-2575. Cocaine metabolism and toxicity. Hisayo O. Morishima, MD, Ph.D., Ext. 5-3884, 5-3499. Perinatal pharmacology and physiology; polydrug abuse. | |||
| http://cpmcnet.columbia.edu/dept/ps/affairs/handbook/handbook0179.html |
| http://www.nottingham.ac.uk/pharmacy/undergraduate/BMSundergrad/PHARMACY/B34HAGTalks2002/COCAINEPRESedited.ppt | |||
| Acute V chronic ?due to altered recptor levels in chronic. ? Main effect at ? -R. IBOGAINE (3). ? ? Cocaine metabolism: Cocaine | |||
| http://www.nottingham.ac.uk/pharmacy/undergraduate/BMSundergrad/PHARMACY/B34HAGTalks2002/COCAINEPRESedited.ppt |
| Research Opportunities in the Division of Clinical Pharmacology | |||
| clinical pharmacology. She has studied the metabolism and effects of nicotine, cocaine and caffeine in the newborn. Dr. Dempsey | |||
| http://www.ucsf.edu/~cpdiv/Faculty/Dempsey.html |
| Program in Medical Biophysics | |||
| William Bosron - Enzymes involved in ethanol and cocaine metabolism are studied using a combination of techniques; steady-state and stopped-flow presteady | |||
| http://www.biophysics.iu.edu/ |
| Brain Imaging | |||
| It still is not known whether the decrease in cerebral metabolism, induced by cocaine and other drugs of abuse, is part of the mechanism by which the drugs | |||
| http://www.addictionrecov.org/paradigm/P_PR_S99/brain_imaging.htm |
| Problems of Forensic Science - Abstracts vol. XLIII | |||
| ENZYMES, PROPERTIES IN RELATION TO COCAINE AND ALCOHOL METABOLISM, AND SPECIFICITIES Karine BERTHOIN, François work was: 1) investigation of cocaine metabolism in association with alcohol intake | |||
| http://www.ies.krakow.pl/wydawnictwo/zzns/abstracts_xliii.htm |
| FORSight: The Forensic Abstracts Journal | |||
| Enzymes, Properties in Relation to Cocaine and Alcohol Metabolism, and Specificities Berthoin-K; Widmer- study were twofold: (1) investigating cocaine metabolism in association with alcohol intake. | |||
| http://www.forensic.gov.uk/forensic/products/forsight/example/index.htm |
| Cocaine Metabolite | |||
| 1977;22:697. 7. Stewart DJ, et al. Cocaine metabolism: Cocaine and nor- cocaine hydrolysis by liver and serum esterases. Clin Pharmacol Ther. 1979;25:464. | |||
| http://www.roche.de/diagnostics/labor/pdf/COCA10_D.pdf |
| Abbott Diagnostics Division - Glossary - C | |||
| abnormalities, such as congenital defects, blood disorders, and inborn errors of metabolism. Cocaine: A substance used as a local anesthetic, also used as a | |||
| http://www.abbottdiagnostics.com/glossary/glossary_c.htm |
| DOE Human Subjects Research 1995 | |||
| More specifically, these studies use positron emission tomography (PET) to evaluate if decreased frontal metabolism in cocaine abusers is related to decreased | |||
| http://www.eml.doe.gov/hsrd/hsr95/BNL28.htm |
| Naltrexone and cocaine craving | |||
| MH - Alcohol Drinking. MH - Animal. MH - Brain. MH - metabolism. MH - Cocaine. MH - administration dosage. MH - Disease Models,Animal. MH - Endorphins. | |||
| http://www.doctordeluca.com/Library/References/Nal_Coke_Crave.htm |
| AD_0020 | |||
| at the outside limit. Exercise has no influence on the metabolism of cocaine (or any other drug). While exercise speeds up metabolism | |||
| http://studenthealth.oregonstate.edu/AnswerSPOT/AlcoholDrugs/AD_0046.htm |
| Pathology of Drug Abuse | |||
| Heart • Liver • Kidneys • Adrenals • Hair • • Fat • Biofluids • Cocaines Effects on Catecholamine Metabolism • General Considerations | |||
| http://shop.store.yahoo.com/spytechagency/13024.html |
| A Psychiatric Times Exclusive! | |||
| antibodies that bind cocaine peripherally, thus preventing it from entering the brain; and the enzyme butyrylcholinesterase, which enhances cocaine metabolism. | |||
| http://www.psychiatrictimes.com/research.html |
| Department of Pharmacology and Toxicology | |||
| Pharmacological manipulations (ie. Cocaine, RNA aptamers) should reveal the relevance of NE modulatory role(s). PUBLICATIONS. (1983) Metabolism of cadaverineand | |||
| http://rcm-medicine.upr.clu.edu/pharm-tox/ortiz.htm |
| PJ Online | New treatments on the pharmacotherapeutic horizon | |||
| its use: could it act fast enough (and metabolise the cocaine before the cocaine reached the brain) and would other pathways of cocaine metabolism be altered | |||
| http://www.pharmj.com/Editorial/20011117/forum/horizon.html |
| Cocaine differentially modulates chemokine production by ... | |||
| Keywords: JOURNAL ARTICLE Chemokines/*BIOSYNTHESIS Cocaine/*PHARMACOLOGY Down-Regulation (Physiology)/DRUG EFFECTS Human HIV Infections/*METABOLISM *HIV-1 | |||
| http://www.aegis.com/pubs/aidsline/2000/may/A0052193.html |
| The Scientist - Brain Imaging Provides A Peek Into The Human ... | |||
| Volkow, director of nuclear medicine at Brookhaven National Laboratory in Upton, NY, has examined how cocaine abuse affects metabolism, dopamine transporters | |||
| http://www.the-scientist.com/yr1998/apr/research_980413.html |
| Cannabinoid activity curtails cocaine craving | |||
| S. Stewart, J. Stress-induced relapse to heroin and cocaine seeking in tance of a crucial enzymatic reaction involved in cell-wall metabolism to methicillin | |||
| http://www.ucsf.edu/cnba/Center/JournalClub/Articles/n_vcannab.pdf |
| Pharmacology of Abused Drugs : Principles, Cannabis, Opiates, ... | |||
| 9 Drug Metabolism * MOSTLY IN LIVER, BUT ALSO IN BLOOD AND morphine, heroin morphine CONVERSION TO ACTIVE METABOLITE: cocaine benzoylecognine, diazepam | |||
| http://www.dhfs.state.wi.us/substabuse/Education/Teleconference/2002presentations/drugpharmacology-part10702.pdf |
| CURRICUKUM VITAE | |||
| Page 7. S. C ASEY L AIZURE P AGE 7 Parker RB, Gades NM, Mandrell TD, Laizure SC: Evaluation of in vivo cocaine metabolism by hepatic carboxylesterase. | |||
| http://dcp.utmem.edu/CV/laizure.pdf |
| Indiana University Department of Biochemistry Molecular Biology | |||
| I am interested in the identification and characterization of esterases involved in cocaine, heroin, opoid ester and CPT-11 metabolism. | |||
| http://www.biochemistry.iupui.edu/personnel/Bosron/ |